Their debut single "Wreckin' Bar (Ra Ra Ra)" was released on 29 November 2010 in the UK where it reached number 157 in the UK Singles Chart and their second single will be "Post Break-Up Sex", released on 24 January 2011.
The Vaccines have been compared to The Jesus & Mary Chain and The Ramones. They describe their influences as "'50s rock 'n' roll, '60s garage and girl groups, '70s punk, '80s American hardcore, C86 and good pop music".
**Plus: The Vaccines are the position No. 3 in the category BEST NEW BANDS OF 2010 of Kool Rock Radio's Annual Report.